Tetrahydrofuran → N-(5-{6-Chloro-5-[3-(2,4-difluorophenyl)ureido]-pyridin-3-yl}-4-methyl-1,3-thiazol-2-yl)acetamide
Reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[F:1][c:2]1[c:3]([N:9]=[C:10]=[O:11])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[NH2:12][c:13]1[cH:14][c:15](-[c:20]2[c:21]([CH3:29])[n:22][c:23]([NH:25][C:26]([CH3:27])=[O:28])[s:24]2)[cH:16][n:17][c:18]1[Cl:19]>>[F:1][c:2]1[c:3]([NH:9][C:10](=[O:11])[NH:12][c:13]2[cH:14][c:15](-[c:20]3[c:21]([CH3:29])[n:22][c:23]([NH:25][C:26]([CH3:27])=[O:28])[s:24]3)[cH:16][n:17][c:18]2[Cl:19])[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-695b18bc09714405a0f28678a2e94618
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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