反应详情

In 3 ml of tetrahydrofuran was dissolved 30 mg of the Compound (30) obtained in Example 30. To the solution was added 30 mg of 10% palladium-carbon, and the mixture was stirred at room temperature for 30 minutes in hydrogen streams. The catalyst was filtered off and washed with tetrahydrofuran. The filtrate and the washing were combined, then the solvent was evaporated off. The residue was subjected to a silica gel column chromatography, followed by elution with hexane-ethyl acetate (2:3) to give 24 mg of the subject Compound (31) as colorless oil.

1. filtrationThe catalyst was filtered off
2. washwashed with tetrahydrofuran
3. customthe solvent was evaporated off
4. washfollowed by elution with hexane-ethyl acetate (2:3)