Tetrahydrofuran → 1-(4-Chloro-3-(2-(2-(dimethylamino)ethylamino)-8-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)phenyl)-3-(3-chloro-4-methoxyphenyl)urea
Reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[Cl:28][c:29]1[c:30]([O:38][CH3:39])[cH:31][cH:32][c:33]([N:35]=[C:36]=[O:37])[cH:34]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([Cl:27])[c:6](-[c:8]2[cH:9][c:10]3[c:11]([n:12][c:13]([NH:16][CH2:17][CH2:18][N:19]([CH3:20])[CH3:21])[n:14][cH:15]3)[n:22]([O:25][CH3:26])[c:23]2=[O:24])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([Cl:27])[c:6](-[c:8]2[cH:9][c:10]3[c:11]([n:12][c:13]([NH:16][CH2:17][CH2:18][N:19]([CH3:20])[CH3:21])[n:14][cH:15]3)[n:22]([O:25][CH3:26])[c:23]2=[O:24])[cH:7]1)[C:36]([NH:35][c:33]1[cH:32][cH:31][c:30]([O:38][CH3:39])[c:29]([Cl:28])[cH:34]1)=[O:37]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-69064f1d9f774bd49107d21f49d1c149
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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