Diethyl Ether → Trifluoroacetic acid

HRID 2322111Notes

Reaction equation

HRID 2322111 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]([CH:9]([CH3:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[C:16]([NH:17][C:18]1([c:21]2[n:22][cH:23][cH:24][cH:25][n:26]2)[CH2:19][CH2:20]1)=[O:27])([CH3:5])([CH3:6])[CH3:28].[CH3:36][CH2:37][O:38][CH2:39][CH3:40].[Cl:41][CH2:42][Cl:43].[F:29][C:30]([C:31](=[O:32])[OH:33])([F:34])[F:35]>>[F:29][C:30]([C:31](=[O:32])[OH:33])([F:34])[F:35].[NH2:7][CH:8]([CH:9]([CH3:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[C:16]([NH:17][C:18]1([c:21]2[n:22][cH:23][cH:24][cH:25][n:26]2)[CH2:19][CH2:20]1)=[O:27]

Participants

6

Reactant 4

HCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 178467785HCID 178467785, compound

Product 2

HCID 6422Trifluoroacetic acidHCID 687311252-amino-3-[(2-methylpropan-2-yl)oxy]-N-(1-pyrimidin-2-ylcyclopropyl)butanamide

Sources & evidence

ORD record
ord-3ffef30de9514e56834373f390067300
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…