2-Oxoglutaric Acid → HCID 14477520, compound

HRID 232227Notes

Reaction equation

[O:1]=[C:2]([CH2:6][CH2:7][C:8]([OH:10])=[O:9])[C:3]([OH:5])=O.[NH:11]1[CH2:15][CH2:14][CH2:13][CH2:12]1>>[N:11]1([C:3](=[O:5])[C:2](=[O:1])[CH2:6][CH2:7][C:8]([OH:10])=[O:9])[CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

Reactant 2

HCID 512-Oxoglutaric Acid

HCID 31268Pyrrolidine

Product 1

HCID 14477520HCID 14477520, compoundYield 51.8%

Procedure

Using 584 mg of 2-oxoglutaric acid and 284 mg of pyrrolidine, there was obtained 412 mg of the subject compound (84), by conducting a reaction and treatment analogous to Example 83, as colorless crystals, m.p. 101°-102° C.

Sources & evidence

ORD record: ord-463186212c2c42f5b64ff3c07535c2f2
Source dataset: uspto-grants-1989_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04851422

Reaction notes

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