3-Oxabicyclo(3.1.0)hexane-2,4-dione → HCID 20031396, compound

HRID 232257Notes

Reaction equation

HRID 232257 reaction equation
[CH2:1]([N:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH2:7]1)[CH2:2][CH2:3][CH2:4][CH3:5].[CH:12]12[CH2:17][CH:16]1[C:15](=[O:18])[O:14][C:13]2=[O:19]>C(O)C>[CH2:1]([N:6]1[CH2:7][CH2:8][N:9]([C:15]([CH:16]2[CH2:17][CH:12]2[C:13]([OH:19])=[O:14])=[O:18])[CH2:10][CH2:11]1)[CH2:2][CH2:3][CH2:4][CH3:5]

Participants

4

Reactant 2

HCID 27347213-Oxabicyclo(3.1.0)hexane-2,4-dioneHCID 27371121-pentylpiperazine

Product 1

HCID 20031396HCID 20031396, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To 100 mL of ethanol is added 1-pentylpiperazine (15.6 g, 0.1 mol) and 11.2 g (0.1 mol) of 3-oxabicyclo[3.1.0]-hexane-2,4-dione. Reflux the reaction and monitor by thin-layer chromatography. Upon completion remove the solvent in vacuo to obtain the title compound.

Workup

  1. temperatureReflux
  2. customthe reaction and monitor by thin-layer chromatography
  3. customUpon completion remove the solvent in vacuo

Sources & evidence

ORD record
ord-0fe2c3b1dd8f4652ac9d496cae8f9b31
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Reaction notes

Loading…