Sodium cyanoborohydride → 3-[Heptyl(2-propenyl)amino]cycloheptanecarbonitrile

HRID 232261Notes

Reaction equation

HRID 232261 reaction equation
O=[C:2]1[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]([C:9]#[N:10])[CH2:3]1.[CH2:11]([NH:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH:12]=[CH2:13].C([BH3-])#N.[Na+]>>[CH2:15]([N:14]([CH2:11][CH:12]=[CH2:13])[CH:2]1[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]([C:9]#[N:10])[CH2:3]1)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

Participants

4

Reactant 3

HCID 5003444Sodium cyanoborohydrideHCID 15629611N-(Prop-2-en-1-yl)heptan-1-amineHCID 157027463-Oxocycloheptane-1-carbonitrile

Product 1

HCID 200313613-[Heptyl(2-propenyl)amino]cycloheptanecarbonitrile

Procedure

In a manner similar to Preparation 8, react 3-oxocycloheptanecarbonitrile with N-(2-propenyl)heptanamine and sodium cyanoborohydride to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 8

Sources & evidence

ORD record
ord-e4900aae235e405bb8d240a56a68bc0f
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Reaction notes

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