HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Chlorophenyl)acetic acid → 4-Chlorophenylacetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Chlorophenyl)acetic acid | HCID 15880 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-Chlorophenylacetyl chloride | HCID 90692 | — |
Reaction Steps
To 100 mL of chloroform is added 4-chlorobenzeneacetic acid (17 g, 0.1 mol) and 24 g (0.2 mol) of thionyl chloride. Reflux the reaction mixture for 3 hours and remove the solvent in vacuo to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04851526 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-b5c0cdb5c426458bb669b3eccacbbbc5 |
| Source note | uspto-grants-1989_07 |