Ethanol → Benzyl 2-[[4-(4-aminophenyl)-1,3-thiazol-2-yl]carbamoyl]pyrrolidine-1-carboxylate

HRID 2322710Notes

Reaction equation

HRID 2322710 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([C:16]([NH:17][c:18]2[s:19][cH:20][c:21](-[c:23]3[cH:24][cH:25][c:26]([N+:29]([O-:30])=[O:31])[cH:27][cH:28]3)[n:22]2)=[O:32])[CH2:13][CH2:14][CH2:15]1.[CH3:36][CH2:37][OH:38].[CH3:39][CH2:40][O:41][C:42]([CH3:43])=[O:44].[Sn:33]([Cl:34])[Cl:35]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([C:16]([NH:17][c:18]2[s:19][cH:20][c:21](-[c:23]3[cH:24][cH:25][c:26]([NH2:29])[cH:27][cH:28]3)[n:22]2)=[O:32])[CH2:13][CH2:14][CH2:15]1

Participants

5

Reactant 4

HCID 702EthanolHCID 8857Ethyl AcetateHCID 24479Stannous ChlorideHCID 765828192-[4-(4-Nitro-phenyl)-thiazol-2-ylcarbamoyl]-pyrrolidine-1-carboxylic acid benzyl ester

Product 1

HCID 57849733Benzyl 2-[[4-(4-aminophenyl)-1,3-thiazol-2-yl]carbamoyl]pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-58b35f9ec1ab4d318e9235ce453db684
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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