Methanol → 1-(4-((2,2-Difluoroethylamino)methyl)thiazol-2-yl)-3-(3-fluorobenzyl)urea
Reaction equation
[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH3:25][OH:26].[F:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][C:7](=[O:8])[NH:9][c:10]2[s:11][cH:12][c:13]([CH2:15][I:16])[n:14]2)[cH:17][cH:18][cH:19]1.[F:20][CH:21]([CH2:22][NH2:23])[F:24]>>[F:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][C:7](=[O:8])[NH:9][c:10]2[s:11][cH:12][c:13]([CH2:15][NH:23][CH2:22][CH:21]([F:20])[F:24])[n:14]2)[cH:17][cH:18][cH:19]1Participants
5
Sources & evidence
- ORD record
- ord-21a32c308e784ef2bf6b4b55d43fb21f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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