Sodium ion → 3-chloro-1-(4-fluorophenyl)pyrazin-2(1H)-one

HRID 2322851Notes

Reaction equation

HRID 2322851 reaction equation
[C:27](=[O:28])([O-:29])[O-:30].[CH:6]1([O:7][c:13]2[c:14](=[O:26])[n:15](-[c:19]3[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]3)[cH:16][cH:17][n:18]2)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12]1.[Na+:31].[Na+:32].[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5]>>[Cl:3][c:13]1[c:14](=[O:26])[n:15](-[c:19]2[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]2)[cH:16][cH:17][n:18]1

Participants

5

Reactant 4

HCID 923Sodium ion2×HCID 19660Carbonate IonHCID 24813Phosphorus oxychlorideHCID 679759613-cyclohexyloxy-1-(4-fluoro-phenyl)-1H-pyrazin-2-one

Product 1

HCID 672214163-chloro-1-(4-fluorophenyl)pyrazin-2(1H)-one

Sources & evidence

ORD record
ord-6e658c4717e146ef8b9ca72758cf16b2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…