3-Aminopyridine → 4-Chloro-2-morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine

HRID 2322857Notes

Reaction equation

HRID 2322857 reaction equation
[Cl:1][c:2]1[n:3][c:4]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[n:5][c:6]([Cl:11])[c:7]1[CH2:8][CH2:9][Cl:10].[NH2:18][c:19]1[cH:20][n:21][cH:22][cH:23][cH:24]1>>[c:2]12[n:3][c:4]([N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[n:5][c:6]([Cl:11])[c:7]1[CH2:8][CH2:9][N:18]2[c:19]1[cH:20][n:21][cH:22][cH:23][cH:24]1

Participants

3

Reactant 2

HCID 100093-AminopyridineHCID 569733604-(4,6-Dichloro-5-(2-chloroethyl)pyrimidin-2-yl)morpholine

Product 1

HCID 592450134-Chloro-2-morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-6c26940bd6704ea4bb473706aa35b7e9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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