HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 20031314, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 20031327 | HCID 20031327 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 20031314 | HCID 20031314 | — |
Reaction Steps
To 100 mL of chloroform is added 24 g (0.2 mol) of thionyl chloride and 27.2 g (0.1 mol) of 1-ethoxy-3-(4-hexylpiperazin-1-yl)-2-propanol. Reflux the reaction and monitor by thin-layer chromatography. Upon completion add saturated aqueous sodium bicarbonate until gas evolution ceases. Dry the organic phase over Na2SO4. Filter the drying agent and evaporate the solvent in vacuo to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04851526 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-fe5e01521abc4e2e84cd520599301c70 |
| Source note | uspto-grants-1989_07 |