p-Fluoronitrobenzene → 1-Methyl-4-(4-nitrophenyl)piperazine

HRID 232295Notes

Reaction equation

HRID 232295 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.F[C:9]1[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][CH:10]=1>>[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:9]2[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][CH:10]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 9590p-FluoronitrobenzeneHCID 531671-Methylpiperazine

Product 1

HCID 28251981-Methyl-4-(4-nitrophenyl)piperazine

Procedure

In a manner similar to Preparation 1, react 1-methylpiperazine with 1-fluoro-4-nitrobenzene to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 1

Sources & evidence

ORD record
ord-0ee734fbfb274efba043ce16321f37f1
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Reaction notes

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