Diethylamine → N,N-Diethyl-N'-[4-(1H-imidazol-1-yl)phenyl]-N'-propyl-1,2-cyclohexanedicarboxamide

HRID 232300Notes

Reaction equation

HRID 232300 reaction equation
[CH2:1]([NH:3][CH2:4][CH3:5])[CH3:2].[N:6]1([C:11]2[CH:16]=[CH:15][C:14]([N:17]([CH2:29][CH2:30][CH3:31])[C:18]([CH:20]3[CH2:25][CH2:24][CH2:23][CH2:22][CH:21]3[C:26](Cl)=[O:27])=[O:19])=[CH:13][CH:12]=2)[CH:10]=[CH:9][N:8]=[CH:7]1>>[CH2:1]([N:3]([CH2:4][CH3:5])[C:26]([CH:21]1[CH2:22][CH2:23][CH2:24][CH2:25][CH:20]1[C:18]([N:17]([C:14]1[CH:15]=[CH:16][C:11]([N:6]2[CH:10]=[CH:9][N:8]=[CH:7]2)=[CH:12][CH:13]=1)[CH2:29][CH2:30][CH3:31])=[O:19])=[O:27])[CH3:2]

Participants

3

Reactant 2

HCID 8021DiethylamineHCID 145556552-[[[4-(1H-imidazol-1-yl)phenyl](propyl)amino]-carbonyl]cyclohexanecarbonyl chloride

Product 1

HCID 14555656N,N-Diethyl-N'-[4-(1H-imidazol-1-yl)phenyl]-N'-propyl-1,2-cyclohexanedicarboxamide

Procedure

In a manner similar to Preparation 16, react diethylamine with 2-[[[4-(1H-imidazol-1-yl)phenyl](propyl)amino]-carbonyl]cyclohexanecarbonyl chloride to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 16

Sources & evidence

ORD record
ord-15e9ec49bc1f498b83619f0ca90fb86e
Source dataset
uspto-grants-1989_07
Patent number
US04851526

Reaction notes

Loading…