Dichloromethane → 4-(4-Methanesulfonyloxyphenyl)-7-[1-(tert-butoxycarbonyl)-5-(piperidinomethyl)indol-2-yl]isoindolinone
Reaction equation
[CH3:41][CH2:42][N:43]([CH2:44][CH3:45])[CH2:46][CH3:47].[CH3:48][S:49]([Cl:50])(=[O:51])=[O:52].[Cl:53][CH2:54][Cl:55].[OH:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]3[c:13]([c:14](-[c:17]4[n:18]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[c:19]5[cH:20][cH:21][c:22]([CH2:26][N:27]6[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]6)[cH:23][c:24]5[cH:25]4)[cH:15][cH:16]2)[C:12](=[O:40])[NH:11][CH2:10]3)[cH:6][cH:7]1>>[O:1]([c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]3[c:13]([c:14](-[c:17]4[n:18]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[c:19]5[cH:20][cH:21][c:22]([CH2:26][N:27]6[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]6)[cH:23][c:24]5[cH:25]4)[cH:15][cH:16]2)[C:12](=[O:40])[NH:11][CH2:10]3)[cH:6][cH:7]1)[S:49]([CH3:48])(=[O:51])=[O:52]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-cf0a91dcc7db4adcb6a13dd349498603
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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