Dimethylformamide → 4-Chloro-7-(2-chloroethoxy)-6-methoxyquinazoline

HRID 2323983Notes

Reaction equation

HRID 2323983 reaction equation
[Cl:1][CH2:2][CH2:3][O:4][c:5]1[c:6]([O:16][CH3:17])[cH:7][c:8]2[c:9](=[O:15])[nH:10][cH:11][n:12][c:13]2[cH:14]1.[O:18]=[CH:19][N:20]([CH3:21])[CH3:22].[S:23]([Cl:24])([Cl:25])=[O:26]>>[Cl:1][CH2:2][CH2:3][O:4][c:5]1[c:6]([O:16][CH3:17])[cH:7][c:8]2[c:9]([Cl:25])[n:10][cH:11][n:12][c:13]2[cH:14]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 135589778HCID 135589778, compound

Product 1

HCID 596829074-Chloro-7-(2-chloroethoxy)-6-methoxyquinazoline

Sources & evidence

ORD record
ord-420416db8f36429bacbe9967d7965b8c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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