Dichloromethane → 4-Bromo-6-methoxyquinolin-3-amine

HRID 2324168Notes

Reaction equation

HRID 2324168 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[cH:9][n:10][c:11]2[cH:12][cH:13][c:14]([O:19][CH3:20])[cH:15][c:16]2[c:17]1[Br:18])([CH3:5])([CH3:6])[CH3:21].[Cl:29][CH2:30][Cl:31].[OH:22][C:23]([C:24]([F:25])([F:26])[F:27])=[O:28]>>[NH2:7][c:8]1[cH:9][n:10][c:11]2[cH:12][cH:13][c:14]([O:19][CH3:20])[cH:15][c:16]2[c:17]1[Br:18]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 68455075(4-Bromo-6-methoxy-quinolin-3-yl)-carbamic acid tert-butyl ester

Product 1

HCID 684539074-Bromo-6-methoxyquinolin-3-amine

Sources & evidence

ORD record
ord-5f2622b4cad646968a4639c186e3f1d9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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