Dimethyl Sulfoxide → HCID 178474623, compound

HRID 2324227Notes

Reaction equation

HRID 2324227 reaction equation
[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[CH3:51][Si:52]([CH3:53])([CH3:54])[Cl:55].[CH3:56][S:57]([CH3:58])=[O:59].[Cl:25][c:26]1[c:27]([F:43])[cH:28][c:29]2[c:30](=[O:42])[c:31]([C:39](=[O:40])[OH:41])[cH:32][n:33]([CH:36]3[CH2:37][CH2:38]3)[c:34]2[n:35]1.[F:1][c:2]1[cH:3][c:4]([N:14]2[C:15](=[O:24])[O:16][CH:17]([CH2:19][NH:20][C:21]([CH3:22])=[O:23])[CH2:18]2)[cH:5][cH:6][c:7]1[NH:8][CH:9]1[CH2:10][NH:11][CH2:12][CH2:13]1>>[F:1][c:2]1[cH:3][c:4]([N:14]2[C:15](=[O:24])[O:16][CH:17]([CH2:19][NH:20][C:21]([CH3:22])=[O:23])[CH2:18]2)[cH:5][cH:6][c:7]1[NH:8][CH:9]1[CH2:10][N:11]([c:26]2[c:27]([F:43])[cH:28][c:29]3[c:30](=[O:42])[c:31]([C:39](=[O:40])[OH:41])[cH:32][n:33]([CH:36]4[CH2:37][CH2:38]4)[c:34]3[n:35]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 6397ChlorotrimethylsilaneHCID 8471TriethylamineHCID 110551427-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acidHCID 178474622HCID 178474622, compound

Product 1

HCID 178474623HCID 178474623, compound

Sources & evidence

ORD record
ord-d4ed1b98da4146e0a58587e86936596b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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