Methanol → 3-chloro-2'-fluoro-N-((tetrahydro-2H-pyran-4-yl)methyl)-2,4'-bipyridin-6-amine
Reaction equation
[Br:1][c:2]1[c:3]([Cl:16])[cH:4][cH:5][c:6]([NH:8][CH2:9][CH:10]2[CH2:11][CH2:12][O:13][CH2:14][CH2:15]2)[n:7]1.[CH3:27][O:28][CH2:29][CH2:30][O:31][CH3:32].[CH3:39][CH2:40][O:41][C:42](=[O:43])[CH3:44].[CH3:45][OH:46].[F:17][c:18]1[n:19][cH:20][cH:21][c:22]([B:24]([OH:25])[OH:26])[cH:23]1.[Na+:33].[Na+:34].[O-:35][C:36](=[O:37])[O-:38]>>[c:2]1(-[c:22]2[cH:21][cH:20][n:19][c:18]([F:17])[cH:23]2)[c:3]([Cl:16])[cH:4][cH:5][c:6]([NH:8][CH2:9][CH:10]2[CH2:11][CH2:12][O:13][CH2:14][CH2:15]2)[n:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-1d538717bb8c47bcbefee0defa09b9a3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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