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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2324713Generated: October 30, 2026

Hydrochloric Acid → [5-Chloro-6-(1-isopropyl-piperidin-4-yloxy)-3-methyl-benzofuran-2-yl]-(4,4-difluoro-piperidin-1-yl)-methanone

https://huagongshe.com/reaction/2324713

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTetrahydrofuranHCID 8028—
ReactantHexafluorophosphateHCID 9886—
ReactantDiisopropylethylamineHCID 81531—
ReactantBenzotriazol-1-yloxy-tris(dimethylamino)phosphoniumHCID 124335—
Reactant4,4-DifluoropiperidineHCID 2758352—
Reactant5-Chloro-6-(1-isopropyl-piperidin-4-yloxy)-3-methyl-benzofuran-2-carboxylic acidHCID 68723620—
Product[5-Chloro-6-(1-isopropyl-piperidin-4-yloxy)-3-methyl-benzofuran-2-yl]-(4,4-difluoro-piperidin-1-yl)-methanoneHCID 68724082—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-0b0f6e05818d4ad4b5a092e4e6d1db88
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)