Hydrochloric Acid → [5-Chloro-6-(1-isopropyl-piperidin-4-yloxy)-3-methyl-benzofuran-2-yl]-(4,4-difluoro-piperidin-1-yl)-methanone
Reaction equation
[CH2:61]([N:62]([CH:63]([CH3:64])[CH3:65])[CH:66]([CH3:67])[CH3:68])[CH3:69].[CH2:70]1[O:71][CH2:72][CH2:73][CH2:74]1.[Cl:1][c:2]1[c:3]([O:15][CH:16]2[CH2:17][CH2:18][N:19]([CH:22]([CH3:23])[CH3:24])[CH2:20][CH2:21]2)[cH:4][c:5]2[c:6]([c:7]([CH3:13])[c:8]([C:10](=[O:11])[OH:12])[o:9]2)[cH:14]1.[ClH:25].[F:26][C:27]1([F:33])[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]1.[P-:34]([F:35])([F:36])([F:37])([F:38])([F:39])[F:40].[n:41]1([O:42][P+:43]([N:44]([CH3:45])[CH3:46])([N:47]([CH3:48])[CH3:49])[N:50]([CH3:51])[CH3:52])[c:53]2[cH:54][cH:55][cH:56][cH:57][c:58]2[n:59][n:60]1>>[Cl:1][c:2]1[c:3]([O:15][CH:16]2[CH2:17][CH2:18][N:19]([CH:22]([CH3:23])[CH3:24])[CH2:20][CH2:21]2)[cH:4][c:5]2[c:6]([c:7]([CH3:13])[c:8]([C:10](=[O:12])[N:30]3[CH2:29][CH2:28][C:27]([F:26])([F:33])[CH2:32][CH2:31]3)[o:9]2)[cH:14]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-0b0f6e05818d4ad4b5a092e4e6d1db88
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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