Dichloromethane → N-(3-(isothiazolo[5,4-b]pyridin-3-ylamino)propyl)-N-((4'-methoxybiphenyl-4-yl)methyl)-1,2-dimethyl-1H-imidazole-4-sulfonamide

HRID 2325091Notes

Reaction equation

HRID 2325091 reaction equation
[CH2:50]([Cl:51])[Cl:52].[CH3:39][n:40]1[c:41]([CH3:49])[n:42][c:43]([S:45](=[O:46])(=[O:47])[Cl:48])[cH:44]1.[CH:30]([N:31]([CH:32]([CH3:33])[CH3:34])[CH2:35][CH3:36])([CH3:37])[CH3:38].[s:1]1[n:2][c:3]([NH:10][CH2:11][CH2:12][CH2:13][NH:14][CH2:15][c:16]2[cH:17][cH:18][c:19](-[c:22]3[cH:23][cH:24][c:25]([O:28][CH3:29])[cH:26][cH:27]3)[cH:20][cH:21]2)[c:4]2[c:5]1[n:6][cH:7][cH:8][cH:9]2>>[s:1]1[n:2][c:3]([NH:10][CH2:11][CH2:12][CH2:13][N:14]([CH2:15][c:16]2[cH:17][cH:18][c:19](-[c:22]3[cH:23][cH:24][c:25]([O:28][CH3:29])[cH:26][cH:27]3)[cH:20][cH:21]2)[S:45]([c:43]2[n:42][c:41]([CH3:49])[n:40]([CH3:39])[cH:44]2)(=[O:46])=[O:47])[c:4]2[c:5]1[n:6][cH:7][cH:8][cH:9]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 27362561,2-Dimethylimidazole-4-sulfonyl chlorideHCID 58726876N1-(isothiazolo[5,4-b]pyridin-3-yl)-N3-((4'-methoxybiphenyl-4-yl)methyl)propane-1,3-diamine

Product 1

HCID 58727123N-(3-(isothiazolo[5,4-b]pyridin-3-ylamino)propyl)-N-((4'-methoxybiphenyl-4-yl)methyl)-1,2-dimethyl-1H-imidazole-4-sulfonamide

Sources & evidence

ORD record
ord-e969ad9b6ab942d28eca0c86691572d5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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