Tetrahydrofuran → 7,8-Difluorochroman
Reaction equation
[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[F:13][c:14]1[cH:15][cH:16][cH:17][c:18]([O:19][CH2:20][C:21]#[CH:22])[c:23]1[F:24].[F:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([c:11]1[F:12])[O:9][CH2:8][CH:7]=[CH:6]2>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([c:11]1[F:12])[O:9][CH2:8][CH2:7][CH2:6]2Participants
4
Sources & evidence
- ORD record
- ord-420ddd8eea0942fcb8cd5b3bcb393d82
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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