2-Methyl-3-butyn-2-ol → 3,4-difluoro-2-[2-fluoro-4-(3-hydroxy-3-methyl-1-butynyl)anilino]-N-(2-hydroxyethoxy)benzamide
Reaction equation
[CH3:25][C:26]([CH3:27])([C:28]#[CH:29])[OH:30].[Cu:31][I:32].[F:1][c:2]1[c:3]([NH:16][c:17]2[c:18]([F:24])[cH:19][c:20]([I:23])[cH:21][cH:22]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][cH:13][c:14]1[F:15]>>[F:1][c:2]1[c:3]([NH:16][c:17]2[c:18]([F:24])[cH:19][c:20]([C:29]#[C:28][C:26]([CH3:25])([CH3:27])[OH:30])[cH:21][cH:22]2)[c:4]([C:5](=[O:6])[NH:7][O:8][CH2:9][CH2:10][OH:11])[cH:12][cH:13][c:14]1[F:15]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-4f3d7015c48d4cc5b42854ee5ae1cf99
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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