Formamide → N-((2,5-Difluorophenyl)(tosyl)methyl)formamide

HRID 2325221Notes

Reaction equation

HRID 2325221 reaction equation
[C:30]([O:31][CH3:32])([CH3:33])([CH3:34])[CH3:35].[CH3:36][C:37]#[N:38].[CH3:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1.[CH:11](=[O:12])[NH2:13].[Cl:14][Si:15]([CH3:16])([CH3:17])[CH3:18].[F:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][c:7]([F:10])[cH:8][cH:9]1.[OH2:29].[c:19]1([CH3:28])[cH:20][cH:21][c:22]([S:25](=[O:26])[OH:27])[cH:23][cH:24]1>>[F:1][c:2]1[c:3]([CH:4]([NH:13][CH:11]=[O:12])[S:25]([c:22]2[cH:21][cH:20][c:19]([CH3:28])[cH:24][cH:23]2)(=[O:26])=[O:27])[cH:6][c:7]([F:10])[cH:8][cH:9]1

Participants

9

Reactant 8

HCID 713FormamideHCID 962WaterHCID 1140TolueneHCID 6342AcetonitrileHCID 6397ChlorotrimethylsilaneHCID 10818p-Toluenesulfinic acidHCID 15413tert-Butyl methyl etherHCID 1376632,5-Difluorobenzaldehyde

Product 1

HCID 22170178N-((2,5-Difluorophenyl)(tosyl)methyl)formamide

Sources & evidence

ORD record
ord-2121994559bb497cb0ea293002b5a3d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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