反应详情

To a solution of 1.9 g (0.031 mol) of zinc dust suspended in 10 mL of HOAc was added 2.3 g (0.012 mol) of the product from Step A. The reaction mixture was refluxed for 1 hour, cooled, filtered and rinsed with acetic acid. The acetic acid solution was poured into 200 mL of H2O and extracted with ethyl acetate (3×50 mL), washed with H2O (2×50 mL), dried over anhydrous magensium sulfate, filtered and concentrated under vacuum to afford 1.9 g of a yellow solid.

1. temperatureThe reaction mixture was refluxed for 1 hour
2. temperaturecooled
3. filtrationfiltered
4. washrinsed with acetic acid
5. additionThe acetic acid solution was poured into 200 mL of H2O
6. extractionextracted with ethyl acetate (3×50 mL)
7. washwashed with H2O (2×50 mL)
8. dry with materialdried over anhydrous magensium sulfate
9. filtrationfiltered
10. concentrationconcentrated under vacuum