(1-Oxo-1,3-dihydro-2H-inden-2-ylidene)acetic acid → (1-Oxo-indan-2-yl)-acetic acid

Participants

Reaction Steps

To a solution of 1.9 g (0.031 mol) of zinc dust suspended in 10 mL of HOAc was added 2.3 g (0.012 mol) of the product from Step A. The reaction mixture was refluxed for 1 hour, cooled, filtered and rinsed with acetic acid. The acetic acid solution was poured into 200 mL of H2O and extracted with ethyl acetate (3×50 mL), washed with H2O (2×50 mL), dried over anhydrous magensium sulfate, filtered and concentrated under vacuum to afford 1.9 g of a yellow solid.

Provenance & Evidence