Carbonate Ion → 2,5-Difluoro-4-[3-(2-hydroxypropan-2-yl)-2-methylpyrrolidin-1-yl]-3-methoxybenzonitrile
Reaction equation
[F:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([F:13])[c:8]([F:12])[c:9]1[O:10][CH3:11].[Li+:24].[Li+:25].[O-:26][C:27](=[O:28])[O-:29].[OH:14][C:15]([CH3:16])([CH3:17])[CH:18]1[CH:19]([CH3:23])[NH:20][CH2:21][CH2:22]1>>[F:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][c:7]([F:13])[c:8]([N:20]2[CH:19]([CH3:23])[CH:18]([C:15]([OH:14])([CH3:16])[CH3:17])[CH2:22][CH2:21]2)[c:9]1[O:10][CH3:11]Participants
5
Sources & evidence
- ORD record
- ord-8959ee3b97b94dd7a0b9a34ec3383c1f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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