Tetrahydrofuran → Ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

HRID 2325580Notes

Reaction equation

HRID 2325580 reaction equation
[CH2:27]([N+:28]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:33][CH2:34][CH2:35][CH3:36])[CH2:37][CH2:38][CH2:39][CH3:40])[CH2:41][CH2:42][CH3:43].[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8](=[O:9])[O:10][CH2:11][CH3:12])[n:13]([Si:16]([CH:17]([CH3:18])[CH3:19])([CH:20]([CH3:21])[CH3:22])[CH:23]([CH3:24])[CH3:25])[cH:14][cH:15]2.[F-:26]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][c:7]1[C:8](=[O:9])[O:10][CH2:11][CH3:12])[nH:13][cH:14][cH:15]2

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 58382073HCID 58382073, compound

Product 1

HCID 53438275Ethyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate

Sources & evidence

ORD record
ord-f9479aa8dec54392a60e689c6a3bb3c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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