HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 178503568, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 3,4-Dihydro-3-thioxo-1,2,4-triazin-5(2H)-one | HCID 1275976 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 178503568 | HCID 178503568 | — |
Reaction Steps
Compound 14a (62 g) dissolved in 2N sodium hydroxide (480 ml) is treated with a solution of methyl iodide (30 ml). After 2 hours at room temperature with agitation, the acetic acid (36 ml) is added drop by drop and the mixture set aside overnight at 0° C. The precipitate formed is filtered, centrifuged, and dried under vacuum at 60° C. in the presence of P2O5 in order to obtain the compound 14b (56.4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05591743 |
| Source dataset | uspto-grants-1997_01 |
| ORD ID | ord-f98bf9984f1f4176a8593f56e7ffc1fd |
| Source note | uspto-grants-1997_01 |