HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 9842804, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | HCID 9842805 | HCID 9842805 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 9842804 | HCID 9842804 | 85% |
Reaction Steps
2-(4-Piperidinyl)-8,8-dipropyl-2-azaspiro[4.5]decane was dissolved in a minimum of anhydrous ethanol and added to a cooled solution of hydrogen chloride in ethanol. On addition of a large volume of ether, a white precipitate formed which was isolated by filteration. The white solid was recrystallized from ethanol or methanol; mp 298°-300° C.; yield 85-90%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05591748 |
| Source dataset | uspto-grants-1997_01 |
| ORD ID | ord-a6ea2741b6e54d86bba8c98464b38109 |
| Source note | uspto-grants-1997_01 |