1-Bromooctane → 3-[4-(2,5-Difluoro-4-methoxyphenyl)piperazin-1-yl]-1-phenylpropan-1-one
Reaction equation
[CH2:1]([O:2][c:3]1[cH:4][cH:5][c:6]([N:7]2[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]2)[cH:13][c:14]1[F:15])[c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1.[CH2:22]([Br:23])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30].[Cl:47][CH2:48][CH2:49][C:50](=[O:51])[c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1.[F:31][c:32]1[c:33]([N:41]2[CH2:42][CH2:43][NH:44][CH2:45][CH2:46]2)[cH:34][c:35]([F:40])[c:36]([O:38][CH3:39])[cH:37]1>>[F:31][c:32]1[c:33]([N:41]2[CH2:42][CH2:43][N:44]([CH2:48][CH2:49][C:50](=[O:51])[c:52]3[cH:53][cH:54][cH:55][cH:56][cH:57]3)[CH2:45][CH2:46]2)[cH:34][c:35]([F:40])[c:36]([O:38][CH3:39])[cH:37]1Participants
5
Sources & evidence
- ORD record
- ord-efbd91ad5d8240f8858388d3d5788550
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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