Dichloromethane → 2-(2-(2H-1,2,3-triazol-2-yl)benzyl)-2,9-diazaspiro[5.5]undecan-1-one

HRID 2326343Notes

Reaction equation

HRID 2326343 reaction equation
[Cl:39][CH2:40][Cl:41].[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38].[n:1]1[n:2](-[c:6]2[c:7]([CH2:8][N:9]3[C:10](=[O:27])[C:11]4([CH2:12][CH2:13][CH2:14]3)[CH2:15][CH2:16][N:17]([C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[CH2:18][CH2:19]4)[cH:28][cH:29][cH:30][cH:31]2)[n:3][cH:4][cH:5]1>>[n:1]1[n:2](-[c:6]2[c:7]([CH2:8][N:9]3[C:10](=[O:27])[C:11]4([CH2:12][CH2:13][CH2:14]3)[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]4)[cH:28][cH:29][cH:30][cH:31]2)[n:3][cH:4][cH:5]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67253417tert-butyl 2-(2-(2H-1,2,3-triazol-2-yl)benzyl)-1-oxo-2,9-diazaspiro[5.5]-undecane-9-carboxylate

Product 1

HCID 672526432-(2-(2H-1,2,3-triazol-2-yl)benzyl)-2,9-diazaspiro[5.5]undecan-1-one

Sources & evidence

ORD record
ord-5398ad2f0ae44c33998dd24cac536374
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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