反应详情

To 2,6-dichlorotoluene (200 g) is added dropwise fuming nitric acid (d=1.52, 206 ml) at 25° to 30° C. After stirring for 30 minutes at room temperature, the mixture is poured into ice-water, extracted with diethyl ether, and the extract is washed with an aqueous sodium hydrogen carbonate solution and then dried. The solvent is distilled off under reduced pressure to give 2,6-dichloro-3-nitrotoluene as yellow crystals (253.2 g).

1. extractionextracted with diethyl ether
2. washthe extract is washed with an aqueous sodium hydrogen carbonate solution
3. customdried
4. distillationThe solvent is distilled off under reduced pressure