Hydroxide → 3-[(2,6-Dichloro-4-hydroxyphenyl)methyl]-1-(4-methoxycyclohexyl)pyrrolidin-2-one

HRID 2326414Notes

Reaction equation

HRID 2326414 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:31])[c:12]([CH2:13][CH:14]2[C:15](=[O:27])[N:16]([CH:19]3[CH2:20][CH2:21][CH:22]([O:25][CH3:26])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:28]([Cl:30])[cH:29]1.[CH3:34][CH2:35][O:36][C:37](=[O:38])[CH3:39].[H:32][H:33].[OH-:40].[OH-:42].[Pd+2:41]>>[OH:8][c:9]1[cH:10][c:11]([Cl:31])[c:12]([CH2:13][CH:14]2[C:15](=[O:27])[N:16]([CH:19]3[CH2:20][CH2:21][CH:22]([O:25][CH3:26])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:28]([Cl:30])[cH:29]1

Participants

6

Reactant 5

HCID 961Hydroxide2×HCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 666218313-[(2,6-Dichloro-4-phenylmethoxyphenyl)methyl]-1-(4-methoxycyclohexyl)pyrrolidin-2-oneHCID 178418361HCID 178418361, compound

Product 1

HCID 666216893-[(2,6-Dichloro-4-hydroxyphenyl)methyl]-1-(4-methoxycyclohexyl)pyrrolidin-2-one

Sources & evidence

ORD record
ord-eb2d3b1cdc2f41a199db4d67d80d2237
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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