Potassium Cation → 5-Chloro-2,3-dihydro-7-[3-(4-piperidinyl)-1,2,4-oxadiazol-5-yl]-4-benzofuranamine

HRID 2326456Notes

Reaction equation

HRID 2326456 reaction equation
[CH3:30][CH:31]([OH:32])[CH3:33].[K+:29].[NH2:1][c:2]1[c:3]([Cl:27])[cH:4][c:5](-[c:11]2[n:12][c:13]([CH:16]3[CH2:17][CH2:18][N:19]([C:22]([O:23][CH2:24][CH3:25])=[O:26])[CH2:20][CH2:21]3)[n:14][o:15]2)[c:6]2[c:7]1[CH2:8][CH2:9][O:10]2.[OH-:28]>>[NH2:1][c:2]1[c:3]([Cl:27])[cH:4][c:5](-[c:11]2[n:12][c:13]([CH:16]3[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[n:14][o:15]2)[c:6]2[c:7]1[CH2:8][CH2:9][O:10]2

Participants

5

Reactant 4

HCID 813Potassium CationHCID 961HydroxideHCID 3776IsopropanolHCID 54520153Ethyl 4-[5-(4-amino-5-chloro-2,3-dihydro-7-benzofuranyl)-1,2,4-oxadiazol-3-yl]-1-piperidinecarboxylate

Product 1

HCID 538340175-Chloro-2,3-dihydro-7-[3-(4-piperidinyl)-1,2,4-oxadiazol-5-yl]-4-benzofuranamine

Sources & evidence

ORD record
ord-b72debcbb13d46eb863cd5aa8fdecba1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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