Dichloromethane → 1,1-Dimethylethyl 4-({[(2-bromo-4-chloro-6-fluorophenyl)amino]-carbonyl}amino)-1-piperidinecarboxylate

HRID 2326567Notes

Reaction equation

HRID 2326567 reaction equation
[Br:1][c:2]1[c:3]([N:10]=[C:11]=[O:12])[c:4]([F:9])[cH:5][c:6]([Cl:8])[cH:7]1.[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[Cl:27][CH2:28][Cl:29].[NH2:13][CH:14]1[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]1>>[Br:1][c:2]1[c:3]([NH:10][C:11](=[O:12])[NH:13][CH:14]2[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]2)[c:4]([F:9])[cH:5][c:6]([Cl:8])[cH:7]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8028TetrahydrofuranHCID 12682914-Amino-1-Boc-piperidineHCID 866189411-Bromo-5-chloro-3-fluoro-2-isocyanatobenzene

Product 1

HCID 596832771,1-Dimethylethyl 4-({[(2-bromo-4-chloro-6-fluorophenyl)amino]-carbonyl}amino)-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-2e10d3c9761b47a2b0abf0863ff4958e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…