1-Methylpiperazine → 4-chloro-N-[4-(2-{4-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethyl]-piperazin-1-yl}-2-oxo-ethyl)-thiazol-2-yl]-benzamide

HRID 2326591Notes

Reaction equation

HRID 2326591 reaction equation
[CH3:29][N:30]1[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[s:10][cH:11][c:12]([CH2:14][C:15](=[O:16])[N:17]3[CH2:18][CH2:19][N:20]([CH2:23][C:24](=[O:25])[OH:26])[CH2:21][CH2:22]3)[n:13]2)[cH:27][cH:28]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[s:10][cH:11][c:12]([CH2:14][C:15](=[O:16])[N:17]3[CH2:18][CH2:19][N:20]([CH2:23][C:24](=[O:25])[N:33]4[CH2:32][CH2:31][N:30]([CH3:29])[CH2:35][CH2:34]4)[CH2:21][CH2:22]3)[n:13]2)[cH:27][cH:28]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 59698876(4-{2-[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetyl}-piperazin-1-yl)-acetic acid

Product 1

HCID 596988354-chloro-N-[4-(2-{4-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethyl]-piperazin-1-yl}-2-oxo-ethyl)-thiazol-2-yl]-benzamide

Sources & evidence

ORD record
ord-b140af32002a4012a540076add487c46
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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