Sodium ion → HCID 58003010, compound

HRID 2326715Notes

Reaction equation

[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[Cl:1][CH2:2][Cl:3].[F:10][c:11]1[cH:12][cH:13][c:14](-[c:17]2[c:18]3[c:23]([cH:24][c:25]([CH:39]([CH3:40])[CH3:41])[c:26]2[CH:27]([c:28]2[cH:29][cH:30][c:31]([C:34]([F:35])([F:36])[F:37])[cH:32][cH:33]2)[OH:38])[O:22][C:21]2([CH2:20][C:19]3=[O:45])[CH2:42][CH2:43][CH2:44]2)[cH:15][cH:16]1.[Na+:53].[OH-:52].[cH:4]1[cH:5][cH:6][n:7][cH:8][cH:9]1>>[F:10][c:11]1[cH:12][cH:13][c:14](-[c:17]2[c:18]3[c:23]([cH:24][c:25]([CH:39]([CH3:40])[CH3:41])[c:26]2[C:27]([c:28]2[cH:29][cH:30][c:31]([C:34]([F:35])([F:36])[F:37])[cH:32][cH:33]2)=[O:38])[O:22][C:21]2([CH2:20][C:19]3=[O:45])[CH2:42][CH2:43][CH2:44]2)[cH:15][cH:16]1

Participants

Reactant 6

HCID 923Sodium ion

HCID 961Hydroxide

HCID 1049Pyridine

HCID 6344Dichloromethane

HCID 8857Ethyl Acetate

HCID 580030305-(4-Fluorophenyl)-6-{hydroxy[4-(trifluoromethyl)phenyl]methyl}-7-isopropylspiro[chromen-2,1'-cyclobutan]-4(3H)-one

Product 1

HCID 58003010HCID 58003010, compound

Sources & evidence

ORD record: ord-92208333961a4791afddc605a3715d10
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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