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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 232673Generated: October 30, 2026

p-Toluenesulfonic acid → Ethyl 2-ethyl-3,4,5,6-tetrafluorobenzoylacetate

https://huagongshe.com/reaction/232673

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Toluenesulfonic acidHCID 6101—
ReactantHCID 54490655HCID 54490655—
ProductEthyl 2-ethyl-3,4,5,6-tetrafluorobenzoylacetateHCID 5393117380.4%

Reaction Steps

Employing diethyl 2-ethyl-3,4,5,6-tetrafluoro-benzoylmalonate (17.2 g) and p-toluenesulfonic acid (0.25 g), the procedure of Reference Example 19 is repeated to give ethyl 2-ethyl-3,4,5,6-tetrafluorobenzoylacetate (11.09 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05591744
Source datasetuspto-grants-1997_01
ORD IDord-d3b857d666c54dab89f305cc690291b1
Source noteuspto-grants-1997_01