1-Butanol → 4-Anilino-5-chloro-2-{4-[2-hydroxy-3-(isopropylamino)propoxy]anilino}pyrimidine
Reaction equation
[CH2:33]([OH:34])[CH2:35][CH2:36][CH3:37].[CH3:38][OH:39].[ClH:32].[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[n:9][c:10]([Cl:15])[n:11][cH:12][c:13]1[Cl:14].[OH:16][CH:17]([CH2:18][O:19][c:20]1[cH:21][cH:22][c:23]([NH2:24])[cH:25][cH:26]1)[CH2:27][NH:28][CH:29]([CH3:30])[CH3:31]>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[n:9][c:10]([NH:24][c:23]2[cH:22][cH:21][c:20]([O:19][CH2:18][CH:17]([OH:16])[CH2:27][NH:28][CH:29]([CH3:30])[CH3:31])[cH:26][cH:25]2)[n:11][cH:12][c:13]1[Cl:14]Participants
6
Sources & evidence
- ORD record
- ord-6038f2e01a74460393758907604318b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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