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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 232768Generated: October 31, 2026

1,4-Dioxa-8-azaspiro(4.5)decane → HCID 67684285, compound

https://huagongshe.com/reaction/232768

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Dioxa-8-azaspiro(4.5)decaneHCID 67435—
ReactantHCID 86735970HCID 86735970—
ProductHCID 67684285HCID 6768428572.34%

Reaction Steps

2α,3α-Epoxy-17β-hydroxy-16β-(4-methyl-1-piperazinyl)-5α-androstane is reacted with 1,4-dioxa-8-azaspiro[4.5]decane as described in Example 3 to give the title compound in a yield of 72.34%, m.p.: 185°-187° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05591735
Source datasetuspto-grants-1997_01
ORD IDord-4e48ed73c1b04dec93a0bec93503b3d3
Source noteuspto-grants-1997_01