Tetrahydrofuran → 3-acetyl-2-benzyl-6-bromo-4-phenyl-2H-isoquinolin-1-one
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9](=[O:28])[c:10]2[cH:11][cH:12][c:13]([Br:27])[cH:14][c:15]2[c:16](-[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:17]1[CH:18]([CH3:19])[OH:20].[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9](=[O:28])[c:10]2[cH:11][cH:12][c:13]([Br:27])[cH:14][c:15]2[c:16](-[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:17]1[C:18]([CH3:19])=[O:20]Participants
3
Sources & evidence
- ORD record
- ord-42c082a4dfb044848c34b4c5f5d03d22
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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