Diphenyl Ether → HCID 15860211, compound

HRID 232788Notes

Reaction equation

HRID 232788 reaction equation
[CH:1]1([O:6][C:7]2[CH:8]=[C:9]([CH2:15][C:16]([NH:18][C:19]3[CH:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:20]=3[O:26]CC=C)=[O:17])[CH:10]=[CH:11][C:12]=2[O:13][CH3:14])[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:30]1(OC2C=CC=CC=2)[CH:35]=CC=C[CH:31]=1>>[CH:1]1([O:6][C:7]2[CH:8]=[C:9]([CH2:15][C:16]([NH:18][C:19]3[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([CH2:35][CH:30]=[CH2:31])[C:20]=3[OH:26])=[O:17])[CH:10]=[CH:11][C:12]=2[O:13][CH3:14])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 7583Diphenyl Ether2×HCID 15860210HCID 15860210, compound2×

Product 1

HCID 15860211HCID 15860211, compound

Procedure

A solution of N-(3-cyclopentyloxy-4-methoxyphenylacetyl)-2-allyloxy-5-chloroaniline (33 grams, 0.079 mol) in 330 milliliters of diphenyl ether was heated at 180° for 6.5 hours. This reaction mixture was combined with a second reaction mixture containing N-(3-cyclopentyloxy-4-methoxyphenylacetyl)-2-allyloxy-5-chloroaniline and 250 milliliters of diphenyl ether which had been heated at 180° for 20 hours.

Workup

  1. temperaturehad been heated at 180° for 20 hours

Sources & evidence

ORD record
ord-8f35b854fff2430ea0f1c4c5690943ee
Source dataset
uspto-grants-1997_01
Patent number
US05591776

Reaction notes

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