Dichloromethane → 1-N-[4-(2-aminoethyl)-3-isoquinolin-6-yl-1,2-oxazol-5-yl]-3-(1H-indol-3-yl)propane-1,2-diamine

HRID 2328172Notes

Reaction equation

HRID 2328172 reaction equation
[Cl:47][CH2:48][Cl:49].[F:40][C:41]([F:42])([F:43])[C:44]([OH:45])=[O:46].[NH2:1][CH:2]([CH2:3][NH:4][c:5]1[c:6]([CH2:20][CH2:21][NH:22][C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[c:7](-[c:10]2[cH:11][c:12]3[cH:13][cH:14][n:15][cH:16][c:17]3[cH:18][cH:19]2)[n:8][o:9]1)[CH2:30][c:31]1[cH:32][nH:33][c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]12>>[NH2:1][CH:2]([CH2:3][NH:4][c:5]1[c:6]([CH2:20][CH2:21][NH2:22])[c:7](-[c:10]2[cH:11][c:12]3[cH:13][cH:14][n:15][cH:16][c:17]3[cH:18][cH:19]2)[n:8][o:9]1)[CH2:30][c:31]1[cH:32][nH:33][c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]12

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67062700HCID 67062700, compound

Product 1

HCID 670627241-N-[4-(2-aminoethyl)-3-isoquinolin-6-yl-1,2-oxazol-5-yl]-3-(1H-indol-3-yl)propane-1,2-diamine

Sources & evidence

ORD record
ord-776ae9c964f2429989a1f2d95db23dab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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