Methanol → (+)-trans-1-(4-Aminomethyl-cyclohexyl)-ethanol

HRID 2328365Notes

Reaction equation

HRID 2328365 reaction equation
[CH2:1]([O:2][C:3](=[O:4])[NH:10][CH2:11][CH:12]1[CH2:13][CH2:14][CH:15]([CH:18]([CH3:19])[OH:20])[CH2:16][CH2:17]1)[c:5]1[cH:6][cH:7][cH:8][cH:9][cH:21]1.[CH3:22][CH2:23][O:24][C:25](=[O:26])[CH3:27].[CH3:31][OH:32].[OH-:28].[OH-:29].[Pd+2:30]>>[NH2:10][CH2:11][CH:12]1[CH2:13][CH2:14][CH:15]([CH:18]([CH3:19])[OH:20])[CH2:16][CH2:17]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 8857Ethyl AcetateHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 20583516HCID 20583516, compound

Product 1

HCID 22481658(+)-trans-1-(4-Aminomethyl-cyclohexyl)-ethanol

Sources & evidence

ORD record
ord-bb784df6e21a4d2a98e8b44ce9701edb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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