Dichloromethane → 1,1-Dimethylethyl 4-{[2-bromo-5-(trifluoromethyl)phenyl]sulfonyl}-1-piperazinecarboxylate

HRID 2328407Notes

Reaction equation

HRID 2328407 reaction equation
[Br:23][c:24]1[c:25]([S:34](=[O:35])(=[O:36])[Cl:37])[cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][cH:29]1.[CH:14]([N:15]([CH2:16][CH3:17])[CH:18]([CH3:19])[CH3:20])([CH3:21])[CH3:22].[Cl:38][CH2:39][Cl:40].[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][N:4]([S:34]([c:25]2[c:24]([Br:23])[cH:29][cH:28][c:27]([C:30]([F:31])([F:32])[F:33])[cH:26]2)(=[O:35])=[O:36])[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 143452tert-Butyl piperazine-1-carboxylateHCID 27786132-Bromo-5-(trifluoromethyl)benzene-1-sulfonyl chloride

Product 1

HCID 666496401,1-Dimethylethyl 4-{[2-bromo-5-(trifluoromethyl)phenyl]sulfonyl}-1-piperazinecarboxylate

Sources & evidence

ORD record
ord-b225ccb4f2e34146a412893e079a2f7b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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