Dichloromethane → 4-(4-Bromo-1H-pyrazol-1-yl)piperidine

HRID 2328410Notes

Reaction equation

HRID 2328410 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][CH:11]([n:14]2[n:15][cH:16][c:17]([Br:19])[cH:18]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:27][CH2:28][Cl:29].[F:20][C:21]([F:22])([F:23])[C:24]([OH:25])=[O:26]>>[NH:8]1[CH2:9][CH2:10][CH:11]([n:14]2[n:15][cH:16][c:17]([Br:19])[cH:18]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 45480278tert-Butyl 4-(4-bromo-1H-pyrazol-1-yl)piperidine-1-carboxylate

Product 1

HCID 521916214-(4-Bromo-1H-pyrazol-1-yl)piperidine

Sources & evidence

ORD record
ord-526548dcc3ba4fe3bfae1f8467151b0d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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