Sodium ion → 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester

HRID 2328675Notes

Reaction equation

HRID 2328675 reaction equation
[CH3:1][c:2]1[c:3]([CH2:13][OH:14])[c:4](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[n:5][o:6]1.[CH3:28][CH2:29][O:30][C:31](=[O:32])[CH3:33].[Cl:17][c:18]1[n:19][cH:20][c:21]([C:22](=[O:23])[O:24][CH3:25])[cH:26][cH:27]1.[H-:15].[Na+:16]>>[CH3:1][c:2]1[c:3]([CH2:13][O:14][c:18]2[n:19][cH:20][c:21]([C:22](=[O:23])[O:24][CH3:25])[cH:26][cH:27]2)[c:4](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[n:5][o:6]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 8857Ethyl AcetateHCID 166653HydrideHCID 254249Methyl 6-chloropyridine-3-carboxylateHCID 2776149(5-Methyl-3-phenyl-1,2-oxazol-4-yl)methanol

Product 1

HCID 665992926-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid methyl ester

Sources & evidence

ORD record
ord-0718f99b18314cf9bbd85c3ea0437597
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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